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Neurogenic inflammation in asthma: 
     Antigen --> fatty cells --> neutrophil -->
                                                                                Eosinophils -->Epithelial cell damage -----
    Stimulation --> macrophage --> T-cell -->

                      Airway contriction
                      Hypersecretion
                      Vascular dilation
                      Plasmatic edema

Neurogenic inflammation --> airway remodeling -- repeat and repeat -- irreversible damage        


Tx: early treatment with steroids

Tx: Pulmicol inhalation + prednisolone     (Symbicort?)                                       

1. diagnosis - pulmonary function test, f/u by PEF/PEV1
2. no cure  - 
3. chronic inflammation - life-long treatment
4. avoid risk factors
5. education (including family)

1. prednisolone 120# bring to home
2. effect: 4 hrs since taking drugs, peak effect at about 12 hrs
3. exacerbation: 8# st. as early as possible
4. double if exacerbing
5. monitor by PEF/PEV1
6. quit high dose prednisolone suddenly within one week