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Three combination:

01 5-HT3 Antagonists (serotonin antagonists)

02 Dexamethasone

03 NK-1 Antagonists (Aprepitant)

 

Palonosetron:

decreasing serotonin receptors

decreasing the 2nd, 3rd days other antiemetics dosages

 

Palonosetron:

01 allosteric binding

02 positive cooperativity

03 receptors internalization

04 long plasma half-life

 

Functional Living Index -  Emesis (FLIE)

 

 

台北六福皇宮

16:10-18:30

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